ISAAC MEDRANO EDINBURG - Isaac Medrano entered eternal rest on October 18, 2020, in Edinburg. Mr. Medrano preceded in death by his grandparents Maria Medrano and Cruz M. Medrano. Mr. Medrano is survived by his his children Isaac C. medrano, Nathan Medrano, Sabian Medrano, and Andrew Salinas; parents Jose Cruz Medrano, Eleamar Garza, step-mom Melisa Medrano, and step-dad Cesar A. Ortez; siblings Cruz Manuel Medrano, Cesar Alberto Ortez II, Isaac Medrano II, Isaias Medrano, Isabel Medrano, Abigail Medrano Aymara Karina Ortez, Aisha Krystal Ortez and Mara Medrano; numerous aunts and cousins.